The Hitchhiker's Guide to the Galaxy book series by Douglas Adams is seriously wonderful. It is a science fiction, humor, and drama all rolled into one. The "trilogy" of five books tells the epic tale of Arthur Dent, Ford Prefect, Zaphod Beeblebrox, Tricia McMillan, and Marvin the Paranoid Android, all of whom travel around the galaxy, back and forth through time and parallel universes.
The story begins with Arthur's house about to be demolished, while the Earth is about to be demolished for a hyperspace bypass. Ford Prefect saves Arthur and they hitch a ride in a Vogon ship, which angers the Vogons. They are released through an airlock and appear in space, and against extreme odds, they are picked up by none other than Zaphod Beeblebrox. From there, they go to Magrathea, where they start trying to find the answer to life, the universe and everything, and once they do, they start looking for the Ultimate Question. They go to the restaurant at the end of the universe, to stop a murderous civilization, and do a lot more, with nothing but their wits and luck, the latter being the abundant.